以VDS为主化疗方案的近期疗效

The resent curative effect or the combination chemocherapy with VDS

摘要: 作者报告以VDS为主的化疗方案治疗多种恶性肿瘤37例。结果总有效率为40.5%，其中肺癌有效率为31.3%，非何杰金氏恶性淋巴瘤有效率为85.7%，食管癌有效率为50.0%；初治病例有效率50.0%，既往经VCR治疗失败病例有效率为38.5%。作者认为VDS对多种恶性肿瘤，特别是对化疗较不敏感的肺腺癌、食道癌等有较好疗效，且与VCR无完全交叉耐药性。其神经毒性低，但要警惕其骨髓毒性。

Abstract: Thirty-seven patients with malignant tumor were treated with the combinationchemocherapy with vindsine(VDS). The total response rates were 40. 5 %. The effective rates of Lung Cancer were 31. 3%, of NHL and Esophagus Cancer were.85. 7 % and 50%. The remission rates of the first treatment cases were 50%, of thecases treated with VCR were 38. 5%. the writer think,VDS was well effect to malignant tumor, special to the Lung Adenocarlinoma and Esophagus Cancer thatwhich hadn't been well raction to chemocherapy, and it wasn't complete cross resistance with VCR. It's neurotoxicity was small, but the restrain to the marrow maybeen on guard aginst.