IAP方案和CAP方案治疗非小细胞肺癌的疗效比较

Compartive study of IAP regime in non-small regime versus CAP cell lung cancer

摘要: 自1993年10月至1996年2月，我院用IAP方案和CAP方案共治疗非小细胞肺癌51例,其中IAP方案组22例（IFO＋ADM＋DDP），获CR1例，PR8例，有效率40．9％（9/22），CAP方案组29例（CTX＋ADM＋DDP），获CR1例，PR10例，总有效率37．9％（11/29），统计学分析两组疗效无显著性差异。本文分析了诸因素对疗效的影响，认为IAP方案同CAP方案一样疗效确切，病人可以耐受，可以作为一般状况好的非小细胞肺癌病人的新辅助治疗方案。

Abstract: The study was conducted to compare the efficacy between IAP regime and CAP regime.From October 1993 to February 1996,A total of 51 patients with stage IIIB or N NSCLC were allocated to either IAP regime(22 cases) or CAP regime(29 cases).All were diagnosed by pathology or cytology,as a result,There were 1 CR and 8 PR(total response rate 40.9%)in IAP group,while 1 CR and 10 PR0.05).The improvement of Karnofsky's status was observed at IAP group and CAP group.The dose-limit toxicity neutropenia was 81.8%in IAP and 71 .8% in CAP group,Grade 3 or 4 neutropenia were 40.1%and 37.0% respectively.Nansea and vomiting were observed,But all patients were tolerable.In conclusion:IAP regime and CAP regime can be recommended as treatment of choice in NSCLC.