乳腺腺纤维瘤10316例临床病理分析
Breast Fibroadenoma
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摘要: 自1954~1990年36例间共收治乳腺腺纤维瘤10316例,均接受手术治疗并经病理证实,其中管型腺纤维瘤3436例占33.3%,围管型腺癌2795例占27.1%,混合型腺纤维瘤3156例占30.6%,分叶型腺纤维瘤526例占5.1%,囊性增生型腺纤维瘤403例占3.9%。患病年龄从9岁~68岁,中位年龄28岁。2/3在发病后2年内就诊。肿瘤最小0.3cm,最大24cm(仅1例,为分叶型腺纤维瘤),大多数≤3cm,占66.5%。病变绝大多数为单发,9228例,占89.5%,多发或双发的1088例,占10.5%。绝大多数经局部切除后治愈,少数病例433例(4.2%)切除后又复发,经再次切除治愈。在收治10316例乳腺腺纤维瘤的同期内有4例腺纤维瘤癌变为管内癌,经手术切除后,预后良好。Abstract: Between 1954 and 1990,10316 patients with breast fibroadenoma were treated and proved by pathology,among which intraductal fibroadonoma(3436 cases) made up to 33. 3%,periductal fibroadenoma (2795 cases) 27.1%,mixed type fibroadenoma(3156 cases) 30.6%,lobulated fibroadenoma (526 cases) 5.1%and cystic hyporplastic fibroadenoma (403 cases)3.90o respectively. Ages of patients ranged from 9 to 68 years old.with the modian age of 28 years old.2/3 patients were treated within 2 years after symptom presented.Tumor size ranged from 0.3cm to 24cm,most of which (66.5%)were smaller than 3cm. Solitary tumor was detected in 9228 cases (89.5%),and two or multiple tumors were detected in 1088 cases (10.5%).Most patients were cured by lumpectomy,while 433 patients (4. 2%)recurred and were cured after resection again. Only 4 cases of carcinoma arising which were intraductal carcinoma were detected among all patients,of which prognosis was good after mastectomy.