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CHOP方案治疗复发性非何杰金氏淋巴瘤38例近期疗效分析

胡东霞, 何家林

胡东霞, 何家林. CHOP方案治疗复发性非何杰金氏淋巴瘤38例近期疗效分析[J]. 肿瘤防治研究, 1997, 24(1): 49-50.
引用本文: 胡东霞, 何家林. CHOP方案治疗复发性非何杰金氏淋巴瘤38例近期疗效分析[J]. 肿瘤防治研究, 1997, 24(1): 49-50.
Hu Dong-xia, . Treatment of Recurrent Non-Hodgkin's Lymphoma (NHL) With CHOP Regimen-Observation of the Short-term Curative Effect in 38 Cases[J]. Cancer Research on Prevention and Treatment, 1997, 24(1): 49-50.
Citation: Hu Dong-xia, . Treatment of Recurrent Non-Hodgkin's Lymphoma (NHL) With CHOP Regimen-Observation of the Short-term Curative Effect in 38 Cases[J]. Cancer Research on Prevention and Treatment, 1997, 24(1): 49-50.

CHOP方案治疗复发性非何杰金氏淋巴瘤38例近期疗效分析

详细信息
  • 中图分类号: R733

Treatment of Recurrent Non-Hodgkin's Lymphoma (NHL) With CHOP Regimen-Observation of the Short-term Curative Effect in 38 Cases

  • 摘要: 本文报道CHOP方案治疗38例复发性非何杰金氏淋巴瘤(NHL)的结果,全部病例均经病理组织学证实。按成都会议方案属中、高度恶性者78.9%,Ⅲ、Ⅳ期病人占65.8%。均经CHOP方案化疗4~11疗程,6疗程以上者占71%,8例加用其它一些抗癌药,9例化疗后予以放疗或手术切除。全组总的缓解率71%,完全缓解率31%,中位缓解期10.3个月。主要毒副反应为消化道反应、白细胞减少及脱发,一般病人都可耐受。作者认为,CHOP方案是一个安全有效的化疗方案,可用于复发性NHL的治疗。

     

    Abstract: The results of chemotherapy with CHOP regimen in 38 recurrent patients of NHL, all pathologically confirmed, were reported. 78.9% of the cases were medi-an-grade or high-grade malignant lymphoma according to Chendo meet's classifica-tions schedule NHL conducted classification (1985), 65.8% of the cases at Ⅲ, Ⅳ stage. The therapy time for the patients treated by CHOP regimen were 4~11 courses, 70% of the cases over 6 courses. All patients were treated by CHOP regi-men,8 cases also applied the other anticarcinogenic drugs, and 9 cases underwent adjuvant radiotherapy or surgient therapy to the residual disease following chemotherapy. The result for the whole group, total response rate was 71%, com-pleted remission rate 31%, and MTS 10.3M. The main side effects including gas-trointestinal toxicity, leucopenia and alopecia were not serve . The authors believe that CHOP is a safe, effective regimen for the patients with relaped case of NHL.

     

  • [1] 黄雪珍, 毛雪芹, 吴晕, 等. ProMACE-MOPP方案治疗NHL(附56例分析). 实用肿瘤杂志, 1992, 7(3): 160.
    [2] 江伟, 祝浩强, 张一欧, 等. CHOP与BEPPA交替治疗进展型恶性淋巴瘤17例近期疗效观察. 癌症, 1991, 10(6): 511.
    [3] 管忠震, 喻俪华, 何友谦, 等. 用CHOP方案治疗NHL103例临床疗效及毒性观察. 癌症, 1989, 8(2): 98.
    [4] 刘淑真, 宋晓红, 杨蔚置, 等. CHOP方案治疗NHL近期疗效分析. 河南肿瘤学杂志, 1993, 6(4): 301.
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出版历程
  • 刊出日期:  1997-02-04

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