扶正抑癌汤合并化疗治疗晚期肺癌临床观察
Clinical Observation of the Combination of the Chemotherapy and the Support healthy Energy Decoction in the Management of Advanced Lung Cancers
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摘要: 本文报道“中药扶正抑瘤汤”并用化疗（简称综合组）治疗晚期肺癌35例同单纯化疗组（简称单化组）30例作了比较，以观察“扶正抑瘤汤”在治疗晚期肺癌的临床作用。全部病例均有病理学依据，Karnofsky（卡氏）评分在60～70分。治疗方法：两组病人均接受化疗至少两个疗程，化疗方案：小细胞肺癌（SCLC）用EP与CMC交替q3W，非小细胞肺癌（NSCLC）用VMP或EMP，每疗程间隔3～4周。综合组加中药扶正抑瘤汤口服。结果：综合组和单化组的有效率（CR＋PR）分别为54.28％、30％，统计学有显著差异（P＜0.05），综合组主要症状的改善优于单化组，化疗引起的副作用小于单化组。提示扶正抑瘤汤配合化疗可以起到增效减毒作用，提高患者的生活质量和近期疗效。Abstract: Therapeutic effect of the support healthy energy decoction plus chemotherapy(group A) and chemotherapy only (group B)in the treatment of advanced lung cancerswas compared. Methods: Comparsion of 65 advancde lung cancers was carried out,group A-35 cases and group B-30 cases. The clinical and pathological results werecompared by the X2 test. Results: The group A gave an overall response rate 54.28%,and the group B 30% (P0.05). Meaniwhile, the group A had a better improvement ofthe clinical symptoms and less side toxicities. Conclusion: In advanced lung cancer casesas treated with combination of chemotherapy and the support healthy energy decoction,clinical results were more satisfied than those of group B.
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Key words:
- The support healthy energy decoction /
- Chemotherapy /
- Advanced lung cancer
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1. Spiesslb, Beahrs OH, Hermanek, P, et al. Lung tumor, UICC TNM. atlas 3rded. Berlin:springer-varlag, 1989:134 2. 汤钊猷主编. 现代肿瘤学. 第1版. 上海:上海医科大学出版社, 1993:612 3. 靖士侠. 抗癌中药及天然药物有效成分研究进展. 中国药学杂志, 1991(2):72
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