卡介苗多糖核酸治疗肺癌高粘滞血症的临床观察

BCG-PSN For The Tretment of Hyperviscosity In Patients With Bronchial Carcinoma

摘要: 对72例肺癌患者的血液流变学（下称血流变）检测，以50例健康人作对照，结果表明肺癌患者存在高粘血症。对其中37例患者除常规治疗外加用卡介苗多糖核酸（BCG—PSN）治疗（试验组），另35例仅作常规治疗（对照组）。观测两组治疗后血流变学变化。结果表明：试验组血流变有明显改善，其中μb、μg、Fig、HCT等指标下降，与健康组相比无明显差异（P>0.05）。而对照组无明显变化。以上提示卡介苗多糖核酸对肺癌高粘滞血症的治疗有积极意义，可作为肺癌的一种辅助治疗手段。

Abstract: Hemorheological changes were assessed in 72 cases of bronehial cancinoma and 50referents. It showed that patieats with bronchial camcinoma had higher levels of viscosityemia. Among them. 37 cases were treated by BCG-PSN combined with the,generaltreatment (the experimertal group), and 35 cases were treated by the general. Treatment (the control group). After treatment, it showed thet the,experimental group hada great improvement in hemorheology. лb, лp， Fig. HCT came down to normal. Thetherapeutic effect of the comtrol group was not so obvious. It suggested that BCGPSN treatment can be beneficied on the,high levels of,viscositymia in bronchial cancinoma.