微量元素与消化道癌Logistic回归分析及临床意义
Logistic Regression Analysis on Trace Elements and Digestive Tract cancer and Clinical significance
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摘要: 本文测定了130例食管癌，100例胃癌，60例结直肠癌，22例肝癌，56例消化道良性疾患。结果表明：消化道癌患者血清中铜，铁含量，铜/锌比显著高于健康人（P＜0.05～P<0.001），锌，钙含量明显低于健康人（P<0.05～P
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关键词:
- 消化道癌 /
- 血清 /
- 微量元素 /
- Logistic回归分析
Abstract: The paper determined serum copper,zine,iron,manganese,calcium levels in esophagus cancer(130 cases). stomatch cancer(100cases). rectal cancer(6Ocases)and liver cancer(22 cases)and various digestive tract benign discases(56 cases). The results showed that serum copper,iron levels,Cu/Zn ratio were significantly higher and zine,calcium levels were significantly lower in digestive tract cancer than in healthy subject and in other digestive tract benign discases(P<0. 05～P<0. 001),stage Ⅲ～Ⅳ and metastatic carcinoma patients copper level,Cu/Zn ratio were significantly higher and zinc level was significantly lower than that in stage Ⅰ～Ⅱ(P<0. 05～P<0. 001),Cu/Zn ratio have a sensitivity 72% on esophagus cancer,68% on stomach cancer,59% on rectal cancer,80% on liver cancer,Cu/Zn ratio can be used as a diagnosis in patients with digestive tract cancer. And it has a certain role in recognizing digestive tract cancer from high risk group. Multi-variable logistic regression analysis showed serum Cu,Cu/Zn ratio elevation maybe the dangerous factors of digestive tract cancer and serum zinc,calcium may have inhibition action to digestive tract cancer.-
Key words:
- Digestive tract cancer /
- Serum /
- Trace elements /
- Logistic regression
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