脑转移瘤几种不同治疗方法疗效分析

The Effects of Different Methods in The Treatment of Brain Metastasis

摘要: 目的回顾性分析脑转移瘤采用单纯放疗（R）、放疗加化疗（R＋C）、立体放射外科加放疗（SRS＋R）治疗效果及影响因素。方法 1993年3月至1998年6月间对收治的脑转移瘤中有61例进行分组治疗观察。结果 6月、12月、＞12月生存率及局部控制率R组分别为54．1％、16．3％、2．7％和16．2％,R＋C组分别为75％、33．3％、25％和41．6％,SRS＋R组分别为83．3％。58．3％、41．6％和91．6％。结论 SRS＋R治疗脑转移瘤在延长患者生存期及局部控制上要优于R和R＋C组。

Abstract: Objective The effects of treat the brain metastasis with radiotherapy along(R),radiotherapy plus chemotherapy (R+C) and stereotactic radiosurgery plus radiotherapy (SRS+R)were analysed retrospectively. Methods From May 1993 to June 1998,61 cases of brain metastasis were studied in 3 groups. Results The 6-,12-,>12-month survival rate and local control rate in group R as 54.1%,16.3%,2.7% and 16.2%,in group R+C as 75.0%,33.3%,25.0% and 41.6%,in gruop SRS+R as 83.3%,58.3%,41.6% and 91.6%. Conclusion SRS+R is superior than R+C and R in the prolong survile period and local control in treat the brain metastase.