进展期胃、大肠癌手术前后腹腔滴注化疗的价值
The Value of Abdominal Drip Chemotherapy before and after Operation of Advanced Gastric and Large lnterstine
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摘要: 目的 了解进展期胃、大肠癌手术前后腹腔穿刺滴注化疗对防治复发和肝转移的价值及此 方法 的可行性。 方法 选择进展期胃、大肠癌门7例,分别随机归入腹腔穿刺滴入化疗组74例,静脉化疗组53例。二组药物、剂量、应用周期相同.前组手术前后直接腹腔穿刺滴入化疗,后组于手术后周围静脉化疗。 结果 腹腔滴注化疗组术后2年“无瘤”生存率、复发转移率与静脉组比较具有显著差异（P＜0．05）。两组未见化疗开发症。 结论 手术前后腹腔滴注化疗对防治进展期胃、大肠癌术后2年复发转移有显著疗效,能有效改善术后2年生存质量,且 方法 简单、易行、安全、实用。Abstract: Objective To study the effect of abdominal paracentesis drip chemotherapy (APDC)before and after operation of advanced gastric and large interstine carcinoma (AGLIC) on preventing relapse and hepatometastasis as well as the practicablity of this method Methods One hundred and twenty seven patients with AGLIC were selected,and randomly divided into APDC'S(n=74) and vein chemotherapy's groups(n=53).The drugs,dosages and using period of the 2 groups were similar.The former were directly given the APDC before and after operations and the later done the peripheral vein chemotherapies after operations. Results After operations,there were significant difference in the rate of both the 2-year“non-tumor” survival and relapse metastasis between the 2 groups after operations(P<0.05).No chemtherapy's comlications developed in both the 2 groups. Conclusion The APDC before and after operation has abvious effect on preventing relapse and metastasis during the 2 years after the AGLIC operations,can effectively improve the existence quality,and is simple,safe and practical.
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