食管贲门癌伴高血压术后非特异性降压效应的临床分析
Clinical Analysis of Non-specific Antihypertensive Effect after Theoperation of Esophago-Cardiac Cancer by Hypertension
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摘要: 目的 探讨食管贲门癌伴高血压术后发生非特异性降压效应的原因和机制。 方法 舒张压＞14．7kpa或收缩压＞24kpa,术前口服降压药物,术中静滴硝酸甘油控制降压。 结果 本组58例,术后1-15天,舒张压≤12．6kpa,收缩压下降12％－18％,且血压下降与术前血压呈正相关。 结论 食管贲门癌伴高血压术后发生非特异性降压效应的原因和机制可能与下列四点有关；（1）应激原解除,应激反应消失。（2）贫血和血液粘滞度降低。（3）胸胃刺激主动脉弓和心肺感受器使减压反射活动增强。（4）手术引起舒血管物质分泌增多和缩血管物质分泌减少。Abstract: Objective To study the reason and mechanism of nonsecific antihypertensive effect after the operation of esophago-cardiac Cancer by hypertension. Methods Diastolic pressure(Dp) was higher than 14.7kpa or systolic pressare (SP) was higher than 24kpa thay reciped antihyperten sive Drugs before the operation or thay were intravanous dripped Nitrogly-Cerinum.during the operation for deliberate hypotension. Results There were 58 cases in this group after the operation.DP was lowered below 12.6kpa.SP was lowered 12%～18%.The effect were lowered in association with blood prassure of fore-operation. Conclusion The following four were reason and mechanism of non-specific antihypertensive effect after the operation of esophago-cardiac cancer by hypertensicn:①thay were done weay with stressor and stress resspones.②anemia lead to blood wiscosity lowered.③intrapulmonary-stomach stimulused aortic arch and heart lung baroreceptor so antihypertensive reflex increased.④the secrine of vasodilator matter increased and the secrine of vasoconstrictor matter decrased.
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