Abstract: Objective To explore the influence of pathology factors on prognosis of colorectal cancer,817 cases with colorectal cancer were selected to study. Methods Using Kaplan Meier s method and Cox model,analysis of survival and prognostic factors were performed to some clinical pathology factors that influenced the prognosis of colorected cancer. Results Result showed that rate of loss to follow-up was 5.14% and the over-all survival rate were 59.92% at 3 years,48.27% at 5 years and 34.02% at 10 years separately...