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肺癌肉瘤3 例报告并文献复习

3 Cases Report and Literature Review of Pulmonary Carcinosarcoma

  • 摘要: 目的 探讨肺癌肉瘤的临床特点、诊断、病理特点、治疗及预后. 方法 对3例肺癌肉瘤进行临床资料回顾性分析,并结合文献对其临床表现、诊断、治疗及预后进行分析. 结果 肺癌肉瘤主要症状为咳嗽、胸痛、血丝痰等,X 线示以周围型居多,还可见肺门、纵隔淋巴结肿大及远处转移.镜下见癌与肉瘤成分共存,光镜及免疫组化分析可确诊.1年生存率64.4%,5年生存率26.7%. 结论 肺癌肉瘤临床特征与肺癌不易区别,预后较肺癌好,外科手术是其主要的诊断和治疗手段.

     

    Abstract: Objective  To explore the clinical characteristics, diagnosis, treatment and prognosis of pulmonary carcinosarcoma ( PCS) . Methods  Three cases with PCS were analysed ret rospectively in their clinicopathological data and light microscopic examinations. At the same time, reviewing literature job was done. Results  The main symptoms of PCS were cough, expectoration, sometimes bloody phlegm. X-ray showed that the peripheral type were the most common type. Margin of the focuses were clear, leafy. The central type were companied by obst ructive pneumonia, atelectasis, and emphysema. The distensive lymph nodes of hilum or mediastium and metastases could also be seen. The 12year survival rate was 64. 4 % and the 52year survival rate was 26. 7 %. Conclusion  PCS is not easy to distingnish with lung cancer, but the prognosis is better then lung cancer. Surgical resection is the main method of diagnosis and treatment .

     

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