男性乳腺癌术后放疗疗效分析

Clinical Analysis of Male Breast Cancer

摘要: 目的探讨男性乳腺癌的临床特征、预后和术后放疗的疗效。方法对22例男性乳腺癌患者进行了随访分析。Ⅰ期3例,Ⅱ期6例,Ⅲ期13例。其中13例手术后未放疗,9例行术后放疗。设胸壁野和区域淋巴结野,每个野肿瘤剂量平均为50Gy左右。11例行辅助化疗。5例接受了内分泌治疗。结果经过72个月中位随访期,5年总生存率为70.1%,无瘤生存率为57.9%。其中IIB+III期患者的5年复发率,手术组为61.31%,术后放疗组为18.75%,差异有显著性意义(P=0.0319)。COX模型多因素分析,腋窝淋巴结转移为唯一的临床预后指标。结论男性乳腺癌术后放疗可减少局部区域的复发。腋窝淋巴结转移为唯一的临床预后指标。

Abstract: Objective To study the clinical and pathological characteristic, the efficiency of post-mastectomy radiation and prognosis of male breast cancer(MBC). Methods Data were collected on 22 men with breast cancer treated at department of Yancheng First People's hospital and Yancheng Second People's hospital from 1981 to 1999. 13 patients underwent surgery only.9 patients received Post-mastectomy radiation, among which 7 patients were irradiated postoperatively at the chest wall (mean dose 50 Gy) and 9 patients r...