Abstract: Objective To research the cyclooxygenase-2 protein expression and its effect in the esophagus cancer. Methods 34 cases of esophagus cancer specimens were examined the expression of COX-2 by immunohistochemical method and Western blotting method. Results The significant positive rates of COX-2 expression in esophagus cancer was 71%,but the significant positive expression in the adenocarcinoma and squamous carcinoma is not significant difference.Statistics test showed that the age,gender,tissue differentiatio...