食管癌患者放疗前后血清sIL-2R 的研究

The Study of sIL-2R in Esophageal Carcinoma Ratients Before and After Radiotherapy

摘要: 目的　探讨食管癌患者放疗前后血清 s IL- 2 R的变化及临床意义。方法　用双抗体夹心 ELISA法检测了 50例食管癌患者放疗前后血清 s IL- 2 R水平。结果　食管癌患者放疗前血清s IL- 2 R水平显著高于正常人 (P<0 .0 0 1 ), 且随病情进展而升高。放疗后血清 s IL- 2 R水平较放疗前显著降低 (P<0 .0 1 )。存活二年的患者放疗结束时, 血清 s IL - 2 R<80 0 u/ml与 80 0 u/ml两组有明显差异 (P<0 .0 1 )。结论　食管癌患者血清 s IL- 2 R明显增高, 并与肿瘤进展, 预后密切相关, 可为肿瘤治疗疗效和判断预后的一个重要指标。

Abstract: Objective To study the clinical significance of the serum sIL-2R level befor and after radiotherapy in the esophageal carcinoma. Methods In this study we used the methods of ELISA to test the serum sIL-2R levels of 80 cases which including 50 cases of esophageal carcinoma and 20 cases of healthy controls. Results The serum sIL-2R level in esophageal carcinoma patients was significantly higher than that of healthy controls (P<0.001).The serum levels of sIL-2R were significantly reduced at the end of rad...