非饮食因素在海岛居民胃癌高发中的作用研究

陈坤; 王建跃; 裘炯良; 张立军; 水黎明

doi:10.3971/j.issn.1000-8578.2714

非饮食因素在海岛居民胃癌高发中的作用研究

浙江大学公共卫生学院流行病教研室; 舟山市疾病控制中心; 310031杭州

详细信息

通讯作者:
陈坤

中图分类号: R735.2
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出版历程
- 收稿日期: 2002-06-25
- 修回日期: 2002-10-16
- 刊出日期: 2003-05-06

Non-dietary factors and gastric cancer in residents of islands

Department of Epidemiology; School of Public Health; Zhejiang University Hangzhou 310031; China

More Information

Corresponding author:
CHEN Kun

摘要

摘要: 目的　研究海岛地区居民非饮食因素与胃癌发病的联系, 为采取有效的防治措施提供科学依据。方法　采用 1∶1频数匹配的病例对照研究法, 随机选择舟山市原发性胃癌新发病例 1 0 3例和人群对照1 33例, 进行胃癌流行病学调查, 并以非条件Logistic回归法分析各因素与胃癌发生的关系。结果　在调整了部分饮食因素的影响后, 饮黄酒史 (OR =1 .81, 95 %CI :1 .2 1～ 2 .71 ), 慢性胃炎史 (OR =7.0 5, 95 %CI :2 .37～ 2 0 .92 ), 父母患胃癌史 (OR =5 .75, 95 %CI :1 .1 3～ 2 9.38), 心理状况差 (OR =1 .95, 95 %CI :1 .2 4～3.0 7)等可明显增加胃癌发生的相对危险性。胃癌一级亲属 (父母 )的遗传度为 37.8± 1 1 .2 (% )。结论　饮黄酒史、慢性胃炎史、癌症家族史及心理因素对海岛居民胃癌的高发有一定的影响
- 胃癌 /
- 遗传度 /
- 病例对照研究 /
- 人群归因危险度
Abstract: Objective To investigate the relationships between non dietary factors and risk of gastric cancer in residents of islands. Methods A frequency matched design of case control study was used. In 103 cases of gastric cancer newly diagnosed in 2001 and 133 controls randomly selected among the residents of islands. Adjusted odds ratios (OR) and 95% confidence intervals (CI) of non dietary factors were estimated using nonconditional logistic regression models. Results Increased risks of gastric cancer ...
- Gastric cancer /
- Heritability /
- Case control study /
- PARc%