乌体林斯注射液合并化疗治疗恶性肿瘤的临床研究

The clinic study for treatment of utilin“s” liquor combining with chemotherapy for the malignant tumors

摘要: 目的　探讨乌体林斯注射液在恶性肿瘤综合治疗中的作用。方法　采用乌体林斯注射液配合化疗与单用化疗对照治疗恶性肿瘤病人 133例, 并对疗效、1年生存率、生存质量及免疫功能进行评价。结果　治疗组近期有效率及 1年生存率均高于对照组, 有显著性差异 (P <0 .0 5 ) ;治疗组生活质量的提高也高于对照组, 有非常显著性差异 (P <0 .0 1) ;治疗组治疗后T细胞亚群及NK细胞活性和免疫球蛋白明显高于治疗前, 有非常显著或显著性差异 (P <0 .0 1或 0 .0 5 ), 而对照组治疗后T细胞亚群及NK细胞活性和免疫球蛋白低于治疗前, 无统计学意义 (P >0 .0 5 )。结论　乌体林斯可通过提高恶性肿瘤患者的细胞免疫和体液免疫功能, 增强机体对化疗药物的耐受性, 从而发挥治疗的协同作用, 达到提高治疗效果和生存质量, 值得临床进一步推广应用。

Abstract: Objective To study the effects of Utilin“s” liquor on synthesis treatment the malignant tumors. Methods 133 cases with malignant tumors were treated with Utilin“s” liquor combining with chemotherapy or only chemotherapy. And to observed the results of treatment,living rate of one year,living quality and immune functions. Results The remission rate and one year s living rate of the trial group was separately 61.76% and 57.35%. and significantly higher...