经单鼻孔-蝶窦内窥镜下切除垂体腺瘤

Endonasal transsphenoidal endoscopic pituitary surgery

摘要: 目的　探讨神经内窥镜在垂体腺瘤切除术中的应用。方法　用神经内窥镜经单鼻孔 -蝶窦切除垂体腺瘤 2 6例, 其中泌乳素腺瘤 7例, 生长激素腺瘤 4例, Cushing综合征 3例, 无功能性腺瘤 12例。结果　内窥镜下全切除肿瘤 2 2例, 近全切除 4例, 视力、视野均较术前改善 ;术后 9例内分泌化验恢复正常, 5例随访激素水平下降 ;2例术后出现一过性脑脊液鼻漏, 1例术后出现尿崩。结论　经单鼻孔 -蝶窦内窥镜下切除垂体腺瘤, 创伤小、并发症少、病人恢复快、疗效可靠。

Abstract: Objective To investigate the application of neuroendoscope in the pituitary surgery. Methods 26 patients with pituitary adenomas were surgical treated through a nostril using rigid endoscopes. 14 patients had hormone-secreting adenomas(7 with prolactinomas, 4 with grouth hormone-secreting adenomas and 3 with Cushing s disease), 12 patients had nonsecreting adenomas. Results 22 underwent total resection and 4 subtotal resection, rapid improvement of vision was noted postoperatively. Among the 14 patients w...