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博来霉素联合凝血酶对恶性血性胸水的疗效观察

吕章春, 胡谷冰, 朱佩贞

吕章春, 胡谷冰, 朱佩贞. 博来霉素联合凝血酶对恶性血性胸水的疗效观察[J]. 肿瘤防治研究, 2002, 29(03): 236-237. DOI: 10.3971/j.issn.1000-8578.2211
引用本文: 吕章春, 胡谷冰, 朱佩贞. 博来霉素联合凝血酶对恶性血性胸水的疗效观察[J]. 肿瘤防治研究, 2002, 29(03): 236-237. DOI: 10.3971/j.issn.1000-8578.2211
LU Zhang-chun, HU Gu-bin, ZHU Pei-zheng. The effect of infusing thrombin into pleural cavity for treatment of malignant pleural effusion[J]. Cancer Research on Prevention and Treatment, 2002, 29(03): 236-237. DOI: 10.3971/j.issn.1000-8578.2211
Citation: LU Zhang-chun, HU Gu-bin, ZHU Pei-zheng. The effect of infusing thrombin into pleural cavity for treatment of malignant pleural effusion[J]. Cancer Research on Prevention and Treatment, 2002, 29(03): 236-237. DOI: 10.3971/j.issn.1000-8578.2211

博来霉素联合凝血酶对恶性血性胸水的疗效观察

详细信息
    通讯作者:

    吕章春

  • 中图分类号: R730.53;R561.5

The effect of infusing thrombin into pleural cavity for treatment of malignant pleural effusion

More Information
    Corresponding author:

    LU Zhang-chun

  • 摘要: 目的 为了观察博来霉素联合凝血酶对恶性血性胸腔积液的治疗效果。方法 采用胸腔穿刺, 置入深静脉留置管引流胸腔积液, 灌注凝血酶, 并以凝血酶 +博来霉素及博来霉素做对照。结果 凝血酶组2 1例有效率 5 2 .4 %, 凝血酶 +博来霉素组 2 1例, 有效率 90 .5 %, 而单纯博来霉素组有效率 71.4 % (各组间比较P <0 .0 5 )。结论 凝血酶是一个安全有效抗恶性胸腔积液药物, 它可安全用于老年人, 它能增强博来霉素的疗效, 二者合用能取得更好地抗胸水效果。

     

    Abstract: Objective To evaluate the tierapeutic effects of infusing thrombin and combined bleomycin into pleural cavity for treatment of malignant pleural effusion. Methods the pleural effusion was drain out from a intrapleural catheter and then infused thrombin,thrombin+bleomycin and bleomycin inspectively and their therapeutic effects were compared in ramdomized trial. Results the response rate of the thrombin groups?the thrombin+bleomycin groups and bleomycin groups were 52.4%?90.5% and 71.4% respectively. Side-e...

     

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出版历程
  • 收稿日期:  2001-06-05
  • 修回日期:  2001-09-19
  • 刊出日期:  2002-05-04

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