Abstract: Objective Nine hundred and ten cases of lower alimentary tract patients were examined by colonofiberscope. Methods Of these, 328 cases were intestinal mucositis,24 ulcerated colitis,79 were polyposis (54 were adenoma and 25 cases were hyperplasia polyposis),74 intestinal carcinoma (30 carcinomas were finally graded Duke A).385 had no symtom and signs.One hundred and twenty two polyposis had been extracted from 79 patients.Of these patients,6 had pre-and local malignant change,after one year follow-up no abnormal had been seem. Conclusion we suggested that colonofiberscopic examination was a safty,sensitive,low expense and save time method for dectection the pre-and early stage of intistinal carcinoma,and may decrease the incidence and mortality rate of this disease.