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磁共振成像指导下宫颈癌调强放疗骨髓保护研究进展

Advances in Bone Marrow Function Protection for Cervical Cancer Intensity-Modulated Radiotherapy Informed by Magnetic Resonance Imaging

  • 摘要: 宫颈癌是常见的妇科恶性肿瘤,放射治疗在其综合治疗中具有重要地位。然而,传统放疗技术常难以避免骨髓损伤,严重影响患者的生活质量和治疗效果。近年来,调强放疗(IMRT)联合磁共振成像(MRI)技术为该问题提供了新的解决方案。IMRT通过优化剂量分布,可降低正常骨髓组织的照射剂量,从而减少骨髓损伤。MRI技术能更精准地定位和监测肿瘤及危及器官(包括骨髓),为放疗计划提供更精确的指导。本文探讨MRI指导下宫颈癌盆腔IMRT对骨髓功能保护的可行性及优势,旨在为宫颈癌放疗的骨髓保护策略提供依据。

     

    Abstract: Cervical cancer is a common gynecological malignancy, and radiotherapy plays a crucial role in its treatment. However, conventional radiotherapy for cervical cancer often leads to bone marrow damage, considerably affecting patients’ quality of life and treatment outcomes. In recent years, the application of intensity-modulated radiotherapy (IMRT) and magnetic resonance imaging (MRI) technologies has provided novel solutions to this issue. IMRT optimizes dose distribution, minimizing radiation exposure to surrounding normal bone marrow tissues and thus considerably reducing damage. MRI allows for accurate tumor localization and monitoring, including organs at risk, such as the bone marrow, and providing precise guidance for radiotherapy. This article analyzes the feasibility and potential benefits of MRI-guided pelvic IMRT for bone marrow protection in cervical cancer, aiming to offer a basis for precise and effective bone marrow protection strategies in cervical cancer radiotherapy.

     

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