Abstract:
Ultrasound-guided local ablation therapy for liver tumors has gained extensive clinical application due to its minimally invasive approach, proven effectiveness, low complication rates, and the ability to repeat treatments. From the initial utilization of Percutaneous Ethanol Injection (PEI) to thermal ablation therapies exemplified by Radiofrequency Ablation (RFA) and Microwave Ablation (MWA), and presently advancing towards emerging techniques such as Irreversible Electroporation (IRE); from conventional ultrasound guidance to contrast-enhanced ultrasound (CEUS) and fusion imaging for precise guidance and assessment; from monotherapy to synergestic therapy strategies; and from early-stage small hepatocellular carcinoma(HCC) to intermediate to large liver cancers, ultrasound-guided interventional therapy has continuously evolved in terms of technological advancements, imaging methods, supplementary strategies, and innovative treatment concepts. The development of ultrasound-guided local ablation of liver cancers has progressed from an initial phase of rapid advancement to a mature stage characterized by further enhancements. This article aims to provide a comprehensive overview of the current status of technical equipment, treatment processes, efficacy, complications, and challenges encountered in ultrasound-guided local ablation for liver tumors, with the objective of offering valuable insights for interventional ultrasound physicians.