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超声引导肝癌消融治疗的现状与思考

经翔

经翔. 超声引导肝癌消融治疗的现状与思考[J]. 肿瘤防治研究. DOI: 10.3971/j.issn.1000-8578.2025.24.1070
引用本文: 经翔. 超声引导肝癌消融治疗的现状与思考[J]. 肿瘤防治研究. DOI: 10.3971/j.issn.1000-8578.2025.24.1070
. Current Status and Challenges of Ultrasound-Guided Ablation Therapy for Liver Cancer[J]. Cancer Research on Prevention and Treatment. DOI: 10.3971/j.issn.1000-8578.2025.24.1070
Citation: . Current Status and Challenges of Ultrasound-Guided Ablation Therapy for Liver Cancer[J]. Cancer Research on Prevention and Treatment. DOI: 10.3971/j.issn.1000-8578.2025.24.1070

超声引导肝癌消融治疗的现状与思考

基金项目: 天津市医学重点学科专科建设项目; 国家自然科学基金

Current Status and Challenges of Ultrasound-Guided Ablation Therapy for Liver Cancer

  • 摘要: 超声引导下肝脏肿瘤局部消融治疗以其微创、疗效确切、并发症少以及可重复治疗的突出优势在临床中获得广泛应用。从最初的PEI到以RFA和MWA为代表的热消融治疗,再到新兴的IRE;从常规US引导到超声造影及融合影像引导和评估;从单一治疗方式到辅助方法及联合治疗策略的应用;从早期的小肝癌到对中-大肝癌治疗的探索,超声引导下消融治疗在技术本身、影像引导方法、辅助策略以及治疗理念等方面始终处于不断更新和发展中,已从初兴的快速发展时期过渡到成熟阶段并进一步完善。本文将通过对超声引导下肝脏肿瘤消融治疗的技术设备、治疗流程、疗效及并发症的现状以及面临的挑战进行概述,以期为介入超声医师提供思考。

     

    Abstract: Ultrasound-guided local ablation therapy for liver tumors has gained extensive clinical application due to its minimally invasive approach, proven effectiveness, low complication rates, and the ability to repeat treatments. From the initial utilization of Percutaneous Ethanol Injection (PEI) to thermal ablation therapies exemplified by Radiofrequency Ablation (RFA) and Microwave Ablation (MWA), and presently advancing towards emerging techniques such as Irreversible Electroporation (IRE); from conventional ultrasound guidance to contrast-enhanced ultrasound (CEUS) and fusion imaging for precise guidance and assessment; from monotherapy to synergestic therapy strategies; and from early-stage small hepatocellular carcinoma(HCC) to intermediate to large liver cancers, ultrasound-guided interventional therapy has continuously evolved in terms of technological advancements, imaging methods, supplementary strategies, and innovative treatment concepts. The development of ultrasound-guided local ablation of liver cancers has progressed from an initial phase of rapid advancement to a mature stage characterized by further enhancements. This article aims to provide a comprehensive overview of the current status of technical equipment, treatment processes, efficacy, complications, and challenges encountered in ultrasound-guided local ablation for liver tumors, with the objective of offering valuable insights for interventional ultrasound physicians.

     

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出版历程
  • 收稿日期:  2024-10-30
  • 录用日期:  2025-02-23
  • 网络出版日期:  2025-02-26

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