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李笑宇. 卵巢癌铂耐药:PFI“二分法”的局限性与可能的改进[J]. 肿瘤防治研究. DOI: 10.3971/j.issn.1000-8578.2024.24.0677
引用本文: 李笑宇. 卵巢癌铂耐药:PFI“二分法”的局限性与可能的改进[J]. 肿瘤防治研究. DOI: 10.3971/j.issn.1000-8578.2024.24.0677
Xiao-yu LI. Platinum resistance in ovarian cancer: Limitations of the PFI binary classification and potential improvements[J]. Cancer Research on Prevention and Treatment. DOI: 10.3971/j.issn.1000-8578.2024.24.0677
Citation: Xiao-yu LI. Platinum resistance in ovarian cancer: Limitations of the PFI binary classification and potential improvements[J]. Cancer Research on Prevention and Treatment. DOI: 10.3971/j.issn.1000-8578.2024.24.0677

卵巢癌铂耐药:PFI“二分法”的局限性与可能的改进

Platinum resistance in ovarian cancer: Limitations of the PFI binary classification and potential improvements

  • 摘要: 卵巢癌是一种较为常见的妇科恶性肿瘤,临床上主要通过无铂间期将复发性卵巢癌分为铂耐药与铂敏感性,分别对应不同的治疗方式及预后。铂耐药性卵巢癌的治疗十分困难,随着研究深入,有研究者提出根据无铂间期的“二分法”存在一定局限性。因此,本文将对复发性卵巢癌的分类、铂耐药性卵巢癌的治疗困境、无铂间期“二分法”的局限性与新的分类思路进行综述,帮助医生更好的了解卵巢癌分类方面的研究进展,从而制定更加有效的治疗策略。

     

    Abstract: Ovarian cancer is a common gynecologic malignancy. In clinical practice, recurrent ovarian cancer is mainly classified into two categories based on platinum-free interval: platinum-resistant and platinum-sensitive, corresponding to different treatment modalities and prognoses. The treatment of platinum-resistant ovarian cancer is extremely challenging. Some scholars have pointed out limitations in the binary classification of platinum-free interval. Therefore, this article will review the classification of recurrent ovarian cancer, the treatment challenges of platinum-resistant ovarian cancer, the limitations of the platinum-free interval binary classification, and new classification perspectives to help physicians better understand the research progress in ovarian cancer classification and develop more effective treatment strategies.

     

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