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儿童肝母细胞瘤外科治疗进展与评述

Progress and Comment on Surgical Treatment of Hepatoblastoma in Children

  • 摘要: 肝母细胞瘤是儿童期最常见的肝脏恶性肿瘤。其发病隐匿,早期症状不典型,通常在查体中发现,就诊时肿瘤体积往往已经较大,以右叶为主,可累及数个肝叶。近年来,随着手术技术进步、新辅助化疗药物的使用及肿瘤MDT团队的建立,肝母细胞瘤患儿的生存率已有较大提高。选择有效且合理的治疗方式对提高肝母细胞瘤患儿的生存率、改善生活质量及减少不良反应具有重要意义。本文将就近年来儿童肝母细胞瘤外科治疗最新进展做简要评述。

     

    Abstract: Hepatoblastoma is the most common malignant tumor of liver in childhood. The onset of hepatoblastoma is insidious and the early symptoms are not typical. It is usually found in physical examination, mainly in the right lobe, and can involve several liver lobes. The tumor volume is often large when seeking treatment. In recent years, with the advancement of surgical techniques, the use of neoadjuvant chemotherapy drugs and the establishment of MDT teams, the survival rate of children with hepatoblastoma has been greatly improved. It's of great significance to select effective and reasonable treatment to improve the survival rate and the quality of life and reduce adverse reactions in children with hepatoblastoma. This paper reviews the progress of surgical treatment of hepatoblastoma in children.

     

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