Abstract:
Objective To investigate the lesions and pathogen infections of the inpatients diagnosed as cutaneous carcinoma, and provide the basis of rational drug use for clinicians.
Methods For the 88 inpatients with cutaneous carcinoma, secretions were collected from the 41 patients whose lesions were ulcerative. VITEK 2 Compact automatic bacterial identification and susceptibility analysis system were applied to perform species identification and drug resistance testing.
Results Thirty-one were positive for the culture of pathogens, among which 18 were Gram-positive bacterium and staphylococcus aureus was the majority; 13 were Gram-negative bacterium and pseudomonas aeruginosa and proteus mirabilis were the majority. The resistant rate of Gram-positive bacterium to macrolide antibiotics was 72.5%. The resistant rate of Gram-negative bacterium to doxycycline reached 100%, and it was also highly resistant to cephalosporin antibiotics. Additionally, four cases of multi-drug resistant bacteria were found.
Conclusion Since bacterial infections are prevalent in the ulcerative lesions of cutaneous carcinoma, clinician should perform pre- and post-operative interventions on the basis of strains identification and susceptibility test results.
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