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腹部纤维母细胞/肌纤维母细胞性肿瘤的PET/CT影像学特点及其应用价值

PET/CT Imaging Characteristics of Abdominal Fibroblastic/Myofibroblastic Tumors and Its Application Value

  • 摘要:
    目的 分析腹部纤维母细胞/肌纤维母细胞性肿瘤的PET/CT影像学表现,提高对该少见病的认识。
    方法 搜集经手术或穿刺病理证实的腹部肌纤维源性肿瘤28例,分析其PET/CT表现。统计学方法采用独立样本t检验、方差齐性检验。
    结果 (1)中间型组有侵袭性纤维瘤病13例、孤立性纤维性肿瘤10例、肌纤维母细胞肿瘤3例;恶性组有纤维肉瘤2例。16例位于腹腔内、12例位于腹膜后,平均直径为12.4 cm。(2)PET/CT发现病灶以局部脂肪浸润或脏器浸润为主,所有病例均无淋巴结转移,3例出现远处转移。(3)侵袭性纤维瘤病、孤立性纤维性肿瘤、肌纤维母细胞肿瘤、纤维肉瘤的SUVmax均值分别为4.9、3.6、5.6和17.9,前三组(中间型)之间差异无统计学意义,但明显低于纤维肉瘤(恶性)。
    结论 PET/CT有助于提示腹部纤维母细胞/肌纤维母细胞性肿瘤的术前TNM分期;SUVmax值有助于肿瘤恶性程度的判断。

     

    Abstract:
    Objective To analyze the PET/CT imaging features of abdominal fibroblastic/myofibroblastic tumors and to improve the understanding of this rare disease.
    Methods We collected 28 cases of abdominal myofibroblastic tumors confirmed by operation or puncture pathology. The PET/CT manifestations of the tumors were analyzed. Statistical methods were independent sample t test and homogeneity of variance test.
    Results (1) There were 13 cases of aggressive fibromatosis, 10 cases of solitary fibrous tumors and 3 cases of myofibroblastoma in intermediate group and 2 cases of fibrosarcoma in malignant group. 16 cases were located in the abdominal cavity and 12 cases were located in the retroperitoneum with an average diameter of 12.4 cm. (2) PET/CT showed that the main lesions were local fat infiltration or organ invasion. No lymph node metastasis was found in any case, and distant metastasis occurred in 3 cases. (3) The mean SUVmax values of aggressive fibromatosis, solitary fibrous tumors, myofibroblastoma and fibrosarcoma were 4.9, 3.6, 5.6 and 17.9. There was no statistical difference among the first three groups (intermediate type), but they were significantly lower than that of fibrosarcoma (malignant type).
    Conclusion PET/CT is helpful for preoperative TNM staging of abdominal fibroblastic/myofibroblastic tumors. SUVmax value is helpful to indicate the malignant degree of tumors.

     

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