Abstract:
Objective To evaluate the efficacy and safety of pseudomonas aeruginosa preparation(PAP) combined with flap point suturing in reducing seroma formation after breast cancer surgery.
Methods We retrospectively analyzed the clinical data of 236 patients after breast cancer resection in our department from March 2015 to March 2017. According to whether pseudomonas aeruginosa preparation was used or not, the patients were divided into two groups: the experimental group (PAP group, n=104) and the control group(n=132). The volume of drainage, the duration of drainage, the incidence of seroma formation, the volume of seroma, the rates of heating and the rates of complications were compared.
Results The experimental group had a lower drainage volume than the control group (486.78±32.54ml vs. 502.56±40.12 ml, P=0.001); the experimental group showed less days of drainage, lower incidence of seroma formation and less volume of seroma (P < 0.05), however, PAP did not increase the rates of heating or complications (P > 0.05).
Conclusion Basis on flap point suturing, the local use of PAP is a feasible and safe option for reducing or preventing seroma formation and promoting wound healing.
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