Abstract: Cancer molecular classification is essential for cancer precision therapy. New molecular classifications of cancers,including breast,ovarian,lung,gastric,pancreatic and colorectal cancers,have been applied in clinical practice. Cancer molecular classification,which is based on comprehensive genomic evaluation,might facilitate the development of treatments tailored to specific subgroups and could enable the delivery of precision medicine to cancer patients. This paper reviews the advances in novel molecular classifications of common solid cancers.