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细胞分化与子宫颈癌

周 颖, 缪 琳, 程 勇, 赵卫东

周 颖, 缪 琳, 程 勇, 赵卫东. 细胞分化与子宫颈癌[J]. 肿瘤防治研究, 2014, 41(03): 280-282. DOI: 10.3971/j.issn.1000-8578.2014.03.018
引用本文: 周 颖, 缪 琳, 程 勇, 赵卫东. 细胞分化与子宫颈癌[J]. 肿瘤防治研究, 2014, 41(03): 280-282. DOI: 10.3971/j.issn.1000-8578.2014.03.018
ZHOU Ying, MIU Lin, CHENG Yong, ZHAO Weidong. Cell Differentiation and Cervical Cancer[J]. Cancer Research on Prevention and Treatment, 2014, 41(03): 280-282. DOI: 10.3971/j.issn.1000-8578.2014.03.018
Citation: ZHOU Ying, MIU Lin, CHENG Yong, ZHAO Weidong. Cell Differentiation and Cervical Cancer[J]. Cancer Research on Prevention and Treatment, 2014, 41(03): 280-282. DOI: 10.3971/j.issn.1000-8578.2014.03.018

细胞分化与子宫颈癌

基金项目: 国家自然科学基金资助项目(81001168,81101525,81272881);安徽高校省级自然科学研究资助项目(KJ2012Z159);安徽省自然科学基金资助项目(1308085MH122);安徽省科技厅2013年重点科研第三批基金资助项目(1301043053)
详细信息
    作者简介:

    周颖(1975-),女,博士,副研究员,主要从事妇科肿瘤的分子诊断及分子机制研究

  • 中图分类号: R737. 33

Cell Differentiation and Cervical Cancer

  • 摘要: 分化障碍在子宫颈癌鳞癌发病机制中作用至关重要,本文就上皮细胞分化的进程、特异分子标识、调控程序加以总结;并对ΔNp63α、ITCH、Notch1、miRNA的异常表达在鳞状上皮细胞分化障碍致细胞癌变中的机制加以综述。

     

    Abstract: Cell differentiation disorders play an important role in the mechanisms of cervical squamous cancer. This paper is to review differentiation disorders involved in the progress, specifi c molecular markers, and regulatory programs of epithelial, as well as abnormal expression of ΔNp63α, ITCH, Notch1 and miRNA in the malignant transformation.

     

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出版历程
  • 收稿日期:  2012-11-15
  • 修回日期:  2013-01-23
  • 刊出日期:  2014-03-24

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