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输尿管癌手术预后的临床病理多因素分析

刘 刚, 关英华, 任小强, 米建强, 张建国

刘 刚, 关英华, 任小强, 米建强, 张建国. 输尿管癌手术预后的临床病理多因素分析[J]. 肿瘤防治研究, 2013, 40(12): 1163-1166. DOI: 10.3971/j.issn.1000-8578.2013.12.012
引用本文: 刘 刚, 关英华, 任小强, 米建强, 张建国. 输尿管癌手术预后的临床病理多因素分析[J]. 肿瘤防治研究, 2013, 40(12): 1163-1166. DOI: 10.3971/j.issn.1000-8578.2013.12.012
LIU Gang, GUAN Yinghua, REN Xiaoqiang, MI Jianqiang, ZHANG Jianguo. Multivariate Analysis of Clinicopathological Factors on Ureter Transitional Cell Carcinoma[J]. Cancer Research on Prevention and Treatment, 2013, 40(12): 1163-1166. DOI: 10.3971/j.issn.1000-8578.2013.12.012
Citation: LIU Gang, GUAN Yinghua, REN Xiaoqiang, MI Jianqiang, ZHANG Jianguo. Multivariate Analysis of Clinicopathological Factors on Ureter Transitional Cell Carcinoma[J]. Cancer Research on Prevention and Treatment, 2013, 40(12): 1163-1166. DOI: 10.3971/j.issn.1000-8578.2013.12.012

输尿管癌手术预后的临床病理多因素分析

详细信息
    作者简介:

    刘刚(1973-),男,本科,主治医师,主要从事泌尿外科疾病的研究

    通讯作者:

    张建国,E-mail:jgzhang@126.com

  • 中图分类号: R737.13

Multivariate Analysis of Clinicopathological Factors on Ureter Transitional Cell Carcinoma

  • 摘要: 目的 综合分析和评价临床病理因素对输尿管癌手术预后的影响。方法 对手术切除51 例输尿管癌7个临床病理因素进行单因素和多因素Cox模型分析。结果 单因素分析表明:年龄(P =0.000)、临床分期(P=0.004)、组织学分级(P=0.000)及手术方式(P=0.048)与输尿管癌手术预后显著相关; 性别(P=0.655)、肿瘤部位(P=0.245)及病理分级(P=0.092)与输尿管癌手术预后无关。多因素分析表明: 临床分期(P=0.021)、组织学分级(P=0.001)、病理分级(P=0.048)及手术方式(P=0.039)是影响输尿管癌手术预后最显著的独立因素。结论 在输尿管癌手术术式设计和选择上,更应该重视和强调根治术,在对输尿管癌术后患者预后评估及术后治疗更应该参考临床分期、组织学分级及病理分级。

     

    Abstract: Objective Our purpose was to evaluate the influence of various clinicopathologic factors on the survival of patients with ureter transitional cell carcinoma(TCC). Methods A computer analysis was performed on 51 patients underwent TCC resection . Results Univariate analysis identifi ed 7 factors that were associated with a significant outcome: Age(P=0.000),clinical stage(P=0.004),histologic type of lesion(P=0.000) and the way of surgical operation(P=0.048). The gender(P=0.655), location of primary lesion(P=0.245) and pathology type of lesion(P=0.092) were not significantly associated with prognosis. However, when the interactive effects of these factors were taken into account,the clinical stage(P=0.021),histologic type of lesion(P=0.001),pathology type of lesion(P=0.048)and way of surgical operation(P=0.039)were selected as the most signifi cant prognostic factors in a multivariate analysis by using the Cox proportional hazard regression model. Conclusion In ureteral cancer surgery procedures design and choice, more importance should be attached to radical operation. On the prognosis improvement of patients with ureteral carcinoma, postoperative evaluation and treatment should refer to clinical stage, histologic type of lesion and pathology type of lesion.

     

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出版历程
  • 收稿日期:  2012-09-20
  • 修回日期:  2013-01-02
  • 刊出日期:  2013-12-24

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