| [1] |
Reynisdottir I,Massagué J. The subcellular locations of p15 (INK4B) and p27 (Kip1) coordinate their inhibitory interactions with cdk4 and cdk2[J].Genes Dev,1997,11(4):492-503.
|
| [2] |
Hofmann WK,Koeffler HP. Important features of myelodysplastic syndrome[J]. Int J Hematol, 2002,76 Suppl 2:222-7.
|
| [3] |
Ng MH,Chung YF,Lo KW,et al. Frequent hypermethylation of p16 and p15 genes in mutiple myeloma[J].Blood,1997,89(7): 2500-6.
|
| [4] |
Higgins JPT,Altman DG.Chapter 8:Assesing risk of bias in included studies[M]//. Higgins JP,Green S. Cochrane handbook for systematic reviews of interventions.Version 5.0.0 [Updated September 2008].Oxford:The Cochrane Collaboration,2008:12-3.
|
| [5] |
Higgins JP,Thompson SG.Quantifying heterogeneity in a meta-analysis[J]. Stat Med,2002,21 (11):1539-58.
|
| [6] |
Uchida T,Knoshita T,Nagai H,et al. Hypermethylation of the p15 INK4B gene in myelodysplastic syndromes[J]. Blood,1997,90(4):1403-9.
|
| [7] |
Quesnel B,Guillerm G, Vereecque R,et al. Methylation of the p15INK4bgene in myelodysplastic syndromes is frequent and acquired during disease progression[J].Blood, 1998,91(8):2985-90.
|
| [8] |
Quesnel B,Fenaux P. P15INK4b gene methylation and myelodysplastic syndromes[J]. Leuk Lymphoma,1999,35(5-6): 437-43.
|
| [9] |
Aoki E,Uchida T,Ohashi H,et al. Methylation status of the p15INK4B gene in hematopoietic progenitors and peripheral blood cells in myelodysplastic syndromes[J]. Leukemia,2000,14(4):586-93.
|
| [10] |
Huang JY,Zeng XC,Chen F,et al. Hypermethylation of P15 Gene in Patients with MDS[J]. Hubei Yi Ke Da Xue Xue Bao,2000, 21(2): 130-2.[黄建英，曾宪昌，陈飞，等.MDS患者P15基因高度甲基化的研究[J]. 湖北医科大学学报,2000,21(2):130- 2.]
|
| [11] |
Ohashi H,Tsushita K,Utsumi M,et al. Relationship between methylation of the p15 gene and ectopic expression of the EVI-1 gene in myelodysplastic syndromes (MDS)[J].Leukemia,2001,15(6):990-1.
|
| [12] |
Preisler HD,Li B,Chen H,et al. P15INK4B gene methylation and expression in normal,myelodysplastic,and acute myelogenous leukemia cells and in the marrow cells of cured lymphoma patients[J].Leukemia, 2001,15(10):1589-95.
|
| [13] |
Tien HF,Tang JH,Tsay W,et al. Methylation of the p15INK4B gene in myelodysplastic syndrome: it can be detected early at diagnosis or during disease progression and is highly associated with leukaemic transformation[J]. Br J Haematol,2001,112(1):148-54.
|
| [14] |
Fan HT,Guo XZ,Tan GX,et al.Study on methylation of p15INK4B in myelodysplastic syndrome[J].Zhongguo Bing Li Sheng Li Xue Za Zhi,2001,17(4):349-52.[范洪涛, 郭秀枝, 谭广销,等. p15基因甲基化在骨髓增生异常综合征中的变化[J].中国病理生理学 杂志,2001,17(4):349-52.]
|
| [15] |
Daskalakis M,Nguyen TT,Nguyen C,et al. Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment[J]. Blood, 2002,100(8): 2957-64.
|
| [16] |
Chen H,Wu S. Hypermethylation of the p15(INK4B) gene in acute leukemia and myelodysplastic syndromes[J].Chin Med J(Engl),2002, 115(7):987-90.
|
| [17] |
Au WY,Fung A,Man C,et al. Aberrant p15 gene promoter methylation in therapy-related myelodysplastic syndrome and acute myeloid leukaemia: clinicopathological and karyotypic associations[J].Br J Haematol,2003,120(6):1062-5.
|
| [18] |
Aoki E , Ohashi H,Uchida T, et al. Expression levels of DNA methyltransferase genes do not correlate with p15INK4B gene methylation in myelodysplastic syndromes[J].Leukemia, 2003,17(9):1903-4.
|
| [19] |
Tong HY,Lin MF.Methylation of p15INK4B geneandits mechanism in patients with myelodysplastic syndrome and leukemia[J]. Zhongguo Bing Li Sheng Li Za Zhi,2004,20(12) :2257-60.[佟红艳, 林茂芳. 骨髓增生异常综合征与白血病细 胞p15INK4B 基因甲基化及机制研究[J]. 中国病理生理杂志,2004,20(12) :2257-60.]
|
| [20] |
Aggerholm A,Holm MS,Guldberg P,et al.Promoter hypermethylation of p15INK4B ,HIC1,CDH1,and ER is frequent in myelodysplastic syndrome and predicts poor prognosis in early-stage patients[J].Eur J Haematol,2006,76(1): 23-32.
|
| [21] |
Wang YP,Song Qing,Li LZ,et al. Deletion of the p15 Gene and promoter methylation in theBone Marrow of patients with myelodysplastic syndromes[J]. Shandong Da Xue Xue Bao(Yi Xue Ban),2009,47(10):106-9.[王亚屏, 宋强, 李丽珍,等. 骨髓增生异常 综合征患者骨髓p15基因的表达缺失与启动子甲基化[J].山东大学学报（医学版）,2009,47(10):106-9.]
|
| [22] |
Eliane FRodrigues,Cíntia BSantos-rebouξas,Mrcia M Gonξalves, et al. Epigenetic alterations ofp15INK4B andp16INK4Agenes in pediatric primary myelodysplastic syndrome[J]. Leukemia & Lymphoma,2010,51(10): 1887-94.
|
| [23] |
Qiao SK, Guo XN , Ren JH , et al. Expression of DNA methyltransferase genes and clinical prognosis in patients with myelodysplastic syndrome[J].Zhongguo Zhong Liu Lin Chuang, 2011,38(17):1011-4.[乔淑凯, 郭晓楠, 任金海,等. DNA 甲基 转移酶基因在MDS患 者中的表达及其临床意义[J]. 中国肿瘤临床, 2011, 38(17):1011-4.]
|
| [24] |
Xu F, Li X, Wu L,et al. Overexpression of the EZH2, RING1 and BMI1 genes is common in myelodysplastic syndromes: relation to adverse epigenetic alteration and poor prognostic scoring[J]. Ann Hematol,2011,90(6):643-53.
|
| [25] |
Ogino A,Yoshino A,Katayama Y,et al.The p15(INK4B)/p16(INK4a)?RB1 pathway is frequently deregulated in human pituitaryadenomas[J]. J Neuropathol Exp Neurol,2005,64(5):398-403.
|
| [26] |
Preisler HD,Li B,Chen H,et al. P15INK4B genemethylation and expression in normal,myelodysplastic,and acute myelogenous leukemia cells and in the marrow cells of cured lymphomapatients[J]. Leukemia, 2001, 15(10):1589-95.
|
| [27] |
WhitmanM. Smads and early developmental signaling by the TGFbeta superfamily[J]. Genes Dev,1998,12(16):2445-62.
|
| [28] |
Ramsfjell V,BorgeOJ,Cui L,et al.Thrombopoietin directly andpntently stimulates multilineage growth andprogenitor cell expansion from primitive (CD34+ CD38-) human bone marrow progenitor cells: distinct and key interactions with the ligandsforc-kit andflt3. and inhibitoryeffects of TGF-beta andTNF-alpha[J].J Immunol,1997,158(11):5169-77.
|
| [29] |
Cameron EE,Baylin SB,Herman JG. p15(INK4B) CpG island methylation in primary acute leukemia is heterogeneous and suggests density as a critical factor for transcriptional silencing[J].Blood,1999,94(7):2445-51.
|
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