Abstract: Objective To explore the clinical epidemiologic characteristics of the elderly patients with colorectal carcinoma (CRC). Methods Analysis and summary was made for 2 810 CRC patients pathologically confirmed in the first affiliated hospital of Guangxi medical university.These patients were divided into the elderly group,mid-aged group and young group. Results The median age was 69 years in the elderly patients and the ratio of male to female was 1.97∶1.Rectum,sigmoid and right colon were the main tumor size.The concomitant ratios of cardiovascular diseases,pulmonary inflammatory diseases,type 2 diabetes and colorectal adenoma in the elderly group,apparently higher than mid-aged group and young group,were 13.46%,4.15%,7.36%,7.20%,respectively.The rate of the obstructive CRC in the elderly group and young group surpassed the one of in the mid-aged group.The patients with synchronous liver metastasis accounted for 11.58% of total elderly patients,and the difference among three groups did not show a statistical significance(P>0.05).The major histological type was tubular adenocarcinoma (86.85%).The highly malignant histological forms including mucinous carcinoma,signet ring cell cancer and undifferentiated carcinoma in the elderly group,was obviously lower than another two groups. Conclusion There are almost twice as many elderly male patients with CRC as elderly female ones in the Guangxi region,and the female percent did not increased evidently.The elderly patients with CRC had these features such as more concomitant preoperative basic diseases,occurred easily colorectal obstruction and with higher-rate colorectal adenoma.The major histological type in the elderly group was tubular adenocarcinoma,and the ratio of the highly malignant histological kinds was very lower,which indicated better prognosis.