Abstract: Objective To observe the therapeutic effect and security of chemotherapy assisted with Jinlong Capsule on patients with gastric cancer. Methods As a randomized,double-blinded,drug-controlled and multicentre study,141 gastric cancer patients diagnosed definitely by histopathology were randomly divided into experiment group (n=70) and control group (n=71).The chemotherapy (FOXFOL4 project or PF project for 2 circles) was used to all of the patients,and patients in experiment group or control group took Jinlong Capsule (4 pills once and 3 times per day) or Zhenqifuzheng Capsule (4 pills once and 3 times per day) orally,espectively.The course of treatment lasted 42 days. Results For the experiment group,the total therapeutic effective rate of the traditional Chinese medicine syndrome was 88.34%,the survival quality and body weight were improved respectively with 46.67% and 48.33%,while 59.68%,19.35% and 19.35% in control group,respectively(P<0.05).For some single symptoms of gastric cancer,the patients in experiment group also ameliorated better than that in control group.The objective therapeutic evaluation of tumor was 16.67% in experiment,while 8.33% in control group (P=0.0676).Furthermore,no serious adverse reaction was found in both two groups. Conclusion It is proved that the chemotherapy assisted with Jinlong Capsule has better therapeutic effect on patients with gastric cancer.