Analysis on Efficacy of Radiation Synchronization and Sequential Zoledronic Acid Treatment to Bone Tumor
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摘要: 目的 分析放疗同步及序贯唑来膦酸对骨转移瘤的治疗效果。方法75例患者，观察组39例在放疗的同时予唑来膦酸治疗，对照组36例放疗结束2～3周后予唑来磷酸治疗。结果放疗同步组与序贯唑来膦酸组有效率分别为92.31%、86.11%，差异无统计学意义(P＞0.05)；疼痛缓解时间平均为7、10天，无痛维持时间平均为65、55天，差异均无统计学意义(P＞0.05)。结论放疗同时或序贯唑来膦酸在骨转移瘤的综合治疗中效果相似，不良反应相似。Abstract: Objective To analysis the efficacy of radiotherapy synchronous or sequential zoledronic acid on bone cancer. Methods Seventy-five patients were divided into two groups. The observation group containing 39 cases were treated with radiation therapy and zoledronic acid at the same time; the control group containing 36 cases were treated with phosphoric acid two weeks after the end of radiotherapy. Results The effective rate in the observation group and control group was 92.31% and 86.11%, respectively; and there were no statistically significant difference in the two groups (P>0.05). The average pain relief time in the observation group and control group was 7 and 10 days, respectively; and the average painless maintenance time was 65 and 55 days, respectively; and there were no statistically significant difference in the two groups (P>0.05). Conclusion Treatment of bone metastases using radiation synchronization or sequential zoledronic acid showed the similar efficacy and side-effects.
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Key words:
- Radiation treatment /
- Bone metastases /
- Zoledronic acid
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