Abstract: Objective To investigate the incidence of cervical lesions in urban,non-resident and rural population of Liuzhou area and to analyze its relationship with living and sanitation habits. Methods Living and sanitation habit were examined using questionnaire and investigation of the high risk factor of the general condition,the result of gynecology physical examination,analysis of the risk factors and the pathological types of cervical lesions. Results Education level,using tubbing,number of sex partner,smoking,drinking,vaginal douching,washing vulva during menstruation,frequency of vitamin food consumption,were statistically different among three populations.The incidence of CIN was 6.11%,11.60% and 10.37%,respectively.Non-resident and rural females were more popular in urban women,and HPV infection was highest in rural female (29.0%).The difference of the incidences of HPV and CIN were found among three populations (P<0.05).After multiple factor non-conditional Logistic regression analysis,early age of first intercourse,multiple sexual partner were the risk factors of cervical lesions.Smoking and drinking showed no correlation with cervical lesions. Conclusion Different living and sanitation habit of urban,rural and non-resident populations may contribute to the difference in incidence of CIN.Individual behavior intervene,especially douching forbidden should be done to reduce the prevalence of CIN.