Abstract: Objective To assess the value of Sure-Touch tactile breast imaging in the diagnosis of breast cancer. Methods One hundred and eleven patients with breast mass were examined separately by the Sure -Touch，ultrasound as well as mammography，and subsequently diagnosed by pathological examination as 64 malignant cases and 47 benign cases.The differences of the three examinations were compared. Results The sensitivity，specificity and accuracy of Sure-Touch were 87.5%，83.0%，and 85.6%,respectively.The accuracy of Sure-Touch for breast mass was not different significantly compared with ultrasound(81.1%).For patients with breast cancer，the results of three examinations were not statistically different from each other.The sensitivity for breast cancer by combined application of Sure-Touch and ultrasound or Sure-Touch and mammography was higher than that by single one. Conclusion Combined application of Sure-Touch and ultrasound or Sure-Touch and mammography ，could further improve the imaging diagnostic consistent rate for breast cancer.