微波消融术对原发性肝癌肝纤维化指标的影响

详细信息

Percutaneous Microwave Coagultion Therapy Influence on Hepatofibrosis of Primary Hepatocellular Carcinoma Serum

1.The Liver Disease Center of The PLA,The 458th Hospital of The PLA,Guangzhou 510602,China；2.Cancer Center,Zhujiang Hospital of Southern Medical University

摘要: 目的探讨微波消融（PMCT）治疗中晚期肝癌对肝纤维化五项指标的影响。方法49例微波消融的原发性肝癌患者，观察治疗前后血清HA、LN、PC-Ⅲ、Ⅳ-C、TGF-β1五项肝纤维化指标水平。结果PMCT治疗后与PMCT治疗前相比，HA、LN、PC-Ⅲ、Ⅳ-C差异无统计学意义，TGF-β1每次均有下降（P＜0.05）。结论 PMCT治疗原发性肝癌对HA、LN、PC-Ⅲ、Ⅳ-C无影响，且对肝纤维化有一定抑制作用。
- 关键词：原发性肝癌 /
- 微波消融 /
- 肝纤维化
Abstract: ObjectiveTo study the influence of the percutaneous microwave coagultion therapy (PMCT) on five hepatofibrosis indexes of middle and advanced hepatocellular carcinoma. MethodsForty-nine cases of primary hepatocellular carcinoma(massive type or nodular type) who had received curation of PMCT，hepatofibrosis index levels of serum HA、LN、PC Ⅲ、IV-C、TGF-β1 were observed before and after therapy. ResultsNo significance difference was observed in relation to HA、LN、PC Ⅲ、IV-C of patients before and after every duration of PMCT.But the TGF-β1 was continuously reduced(P＜0.05). Conclusion The HA、LN、PC-Ⅲ、Ⅳ-C were not significantly changed after PMCT, but the TGF-β1 was continuously reduced.
- Key words：Primary hepatocellular carcimona /
- PMCT /
- Hepatofibrosis