新疆2 019例汉族、维吾尔族乳腺癌临床病理资料分析
Clinicopathologic Analysis of 2 019 Breast Cancer Patients with Han and Uygur Nationalities in Xinjiang Area
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摘要: 目的 探讨新疆汉族、维吾尔族（维族）乳腺癌患者临床和病理特点，为防治工作提供基础数据。方法 对2004—2008年期间经病理组织学证实，2 019例手术治疗的汉、维族乳腺癌患者资料进行统计分析。结果 2 019例中汉族病例1 592例（78.85%），维族病例427例(21.15%)，维汉之比为1：3.73。与汉族乳腺癌病例相比：初潮较晚、绝经较早、生育次数较多、哺乳时间较长、原发肿块较大、腋窝淋巴结转移数目较多、孕激素受体（progesterone，PR）阳性表达率较低、年轻乳腺癌及三阴性乳腺癌（triple negative breast cancer，TNBC）比例较高是维族乳腺癌病人的特点。结论 新疆汉族、维族乳腺癌患者临床和病理特征不同。Abstract: Objective To investigate the clinicopathological characteristics of breast cancer patients with Han and Uygur nationalities，and provide basic information for different prevention strategies in Xinjiang Area. Methods A retrospective study was conducted for 2 019 breast cancer patients with Han and Uygur nationalities confirmed by pathological information during 2004 to 2008. Results Patients of Han and Uygur nationalities in the study were 1 592（78.85%）and 427 (21.15%)，respectively.The ratio was 3.73∶1.Compared with Han nationality，Uygur patients had characteristics of later age of menarche，earlier age of menopause，more times of delivery，more cumulative time of lactation，larger tumor size，more number of involved axillary lymph nodes，low ratio of the expression of progesterone receptor，high ratio of young age and triple-negative breast cancer. Conclusion Breast cancer patients of Han and Uygur nationalities had different clinicopathological characteristics in Xinjiang.
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