Abstract: Objective Two chemotherapies were compared in order to investigate the better chemothrapy in concurrent chemotherapy and radiotherapy of cervial cancer. Methods Two hundred and thirty-eight patients with advanced cervical cancer were randomly divided into BIP group（133 cases）and PF group（105 cases).The survival rates and toxicity of these two groups were compared. Results The 2-year survival rate and progression-free survival rate of BIP group was 76.7%（102/133） and 70.7%（94/133） respectively.The 2-year survival rate and progression-free survival rate of PF group was 63.8%（67/105） and 57.1%（60/105） respectively.Signifcant differences were found between these two groups（P＜0.05）. Ⅲ~Ⅳ degree myelosuppression occurred more frequently in the BIP group than in PF group（P＜0.05）.However the long-term toxicity of these two groups has no signifcant difference. Conclusion Of the two chemotherapies used in concurrent chemotherapy and radiotherapy of cervix cancer,BIP proceded PF in survival rate,but it has severer marrow toxicity.The long-term toxicity of these two groups has no signifcant difference.