Abstract: To study the relationship between colorectal adenoma with dysplasia and cancerization and clinico pathological characteristics. Methods The relationships were retrospectively analyzed between colorectal adenoma with dysplasia and cancerization and the tumor size, location, appearance, pathological type of colorectal adenoma. Results In all cases, carcinomatous incidence was 5.4% (42 cases).The rate of malignant villous adenoma was high and malignant tubular adenoma was low. The incidence of malignant adenoma was significantly higher in rectum adenoma than that in the right colon adenoma (P<0.05). The rate of colorectal adenoma with dysplasia and cancerization was increased with the size increasing. The incidence of cancerization was higher in flat adenoma than that in stemmed adenoma. Carcinomatous rate of colorectal adenoma was augmented as the degree of dysplasia increased(P<0.05). Conclusion Many factors, such as the size, location, appearance, pathological type and the degree of dysplasia of colorectal adenoma were related with colorectal cancerization.