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混合性血管内皮瘤1 例报告及文献复习

常 青, 毛永荣, 吴昌鸣, 王明伟

常 青, 毛永荣, 吴昌鸣, 王明伟. 混合性血管内皮瘤1 例报告及文献复习[J]. 肿瘤防治研究, 2007, 34(11): 868-870. DOI: 10.3971/j.issn.1000-8578.1409
引用本文: 常 青, 毛永荣, 吴昌鸣, 王明伟. 混合性血管内皮瘤1 例报告及文献复习[J]. 肿瘤防治研究, 2007, 34(11): 868-870. DOI: 10.3971/j.issn.1000-8578.1409
CHANG Qing, MAO Yong-rong, WU Chang-ming, WANG Ming-wei. Clinicopathologic Features of 1 Case of Composite Haemangioendothel ioma and Relative Literatures Review[J]. Cancer Research on Prevention and Treatment, 2007, 34(11): 868-870. DOI: 10.3971/j.issn.1000-8578.1409
Citation: CHANG Qing, MAO Yong-rong, WU Chang-ming, WANG Ming-wei. Clinicopathologic Features of 1 Case of Composite Haemangioendothel ioma and Relative Literatures Review[J]. Cancer Research on Prevention and Treatment, 2007, 34(11): 868-870. DOI: 10.3971/j.issn.1000-8578.1409

混合性血管内皮瘤1 例报告及文献复习

详细信息
    通讯作者:

    常 青

  • 中图分类号: R732. 2

Clinicopathologic Features of 1 Case of Composite Haemangioendothel ioma and Relative Literatures Review

More Information
    Corresponding author:

    CHANG Qing

  • 摘要: 目的 探讨混合性血管内皮瘤临床病理特点及免疫组化表型。方法 对1例混合性血管内皮瘤病理组织学及免疫组化表型中的CD31、CD34、VⅢ因子、VWF、PCK、Vimentin、EMA进行观察并复习相关文献。结果 巨检:送检骨骼肌带筋膜,肌间见31个灰白色结节,直径0.6~2.5cm,切面灰白色鱼肉状。镜检:瘤组织成分复杂,有网状型血管内皮瘤、上皮性血管内皮瘤及梭形细胞血管内皮瘤成分。免疫组化表型为血管来源肿瘤。结论 混合性血管内皮瘤属极其罕见低度恶性肿瘤,成分多样。免疫组化表型有助于其诊断分析。

     

    Abstract: Objective  To explore the clinicopathologic features of one case of composite haemangioendothelioma and its immunohistochemistry expression. Methods  Monoclonal antibodies including CD31, CD34, Factor VIII, VWF(von Willebrand Factor), PCK, Vimentin and EMA was used to detect the expression of this case and the relative literatures were reviewed. Results  Macroscopy showed that the speciman was a piece of skeletal muscle with fascia. Thirty-one gray nodules whose diameter were 0. 6 to 2. 5 cm could be seen. Microscopy : the neoplasm was consisted of complex admixture of retiform haemangioendothelioma, epithelioid haemangioendothelioma and spindle cell haemangioma. The lesions are positive for vascular markers ( CD31, CD34, Factor VIII, VWF ) . Conclusion  The composite haemangioendothelioma was a very rare low-grade malignant tumor whose component s were diverse. Immunohistochemistry expressions could help us diagnose the tumor.

     

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出版历程
  • 收稿日期:  2007-04-18
  • 修回日期:  2007-09-09
  • 刊出日期:  2007-11-04

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