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GP方案与FLEP方案治疗晚期胰腺癌的疗效比较

李平, 李兆申, 王雅杰

李平, 李兆申, 王雅杰. GP方案与FLEP方案治疗晚期胰腺癌的疗效比较[J]. 肿瘤防治研究, 2002, 29(01): 71-72. DOI: 10.3971/j.issn.1000-8578.133
引用本文: 李平, 李兆申, 王雅杰. GP方案与FLEP方案治疗晚期胰腺癌的疗效比较[J]. 肿瘤防治研究, 2002, 29(01): 71-72. DOI: 10.3971/j.issn.1000-8578.133
LI Ping, LI Zhao-shen, WANG Ya-jie. Comparative study of gemcitabine plus cisplatin and FLEP regimen in the treatment of advanced pancreatic cancer[J]. Cancer Research on Prevention and Treatment, 2002, 29(01): 71-72. DOI: 10.3971/j.issn.1000-8578.133
Citation: LI Ping, LI Zhao-shen, WANG Ya-jie. Comparative study of gemcitabine plus cisplatin and FLEP regimen in the treatment of advanced pancreatic cancer[J]. Cancer Research on Prevention and Treatment, 2002, 29(01): 71-72. DOI: 10.3971/j.issn.1000-8578.133

GP方案与FLEP方案治疗晚期胰腺癌的疗效比较

详细信息
    通讯作者:

    李平

  • 中图分类号: R735.9;R730.53

Comparative study of gemcitabine plus cisplatin and FLEP regimen in the treatment of advanced pancreatic cancer

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    Corresponding author:

    LI Ping

  • 摘要: 目的比较GP(健择+DDP)与FLEP(CF、5-Fu、EPI、DDP)方案治疗晚期胰腺癌的近期疗效与不良反应。方法将40例晚期胰腺癌随机分为治疗组和对照组,分别给予GP与FLEP方案化疗2个周期,按WHO标准评定疗效和不良反应。结果两组有效率(CR+PR)分别为30%和15%,治疗组高于对照组(P<0.05),两组的毒副反应相似。不良反应主要为骨髓抑制和胃肠道反应。结论健择加顺铂是治疗晚期胰腺癌的一种安全有效的化疗方案。

     

    Abstract: Objective To compare the efficacy and toxicity of gemcitabine plus cisplatin and FLEP(5-fluorouracil,epirubicin and cisplatin) regimen for advanced pancreatic cancer. Methods The clinical data of 40 case with advanced pancreatic cancer treated with GP(20 cases ) and FLEP (20 cases) regimen were analysed . Results The response rate was 30% in patients with GP, 15% in those with FLEP regimen .The side effect and toxicity of two groups was similar.The main toxicity was myelosuppression and gastrointestinal tr...

     

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出版历程
  • 收稿日期:  2001-02-02
  • 修回日期:  2001-09-20
  • 刊出日期:  2002-01-04

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