Abstract: Objective To study the histopathological characteristics,diagnosis,differential diagnosis and prognosis of Granular cell tumor of the breast. Methods Two cases of Granular cell tumor of the breast were studied by histopathological observation and immunohistochemical staining. Results No special clinical situations were found in two cases and the tumor was charsterized by clear cell boundary,aboundant cytoplasm, full of acidophilic granules and it also infiltrated beyond the edge of the main tumor. Immunohis...