Abstract: Objective 　To investigate the clinical characteristics and prognosis of multiple primary malignant neoplasms with lung cancer (MPMNs) . Methods 　Lung cancer patient s who hospitalized in our department from 1987 to 2002 were accumulated and those diagnosed as MPMNs were analyzed. Results 　There were eleven MPMNs patients, including 10 males and 1 female. The ratio to total lung cancer patient s was 0. 6 % (11/ 1802) . Five of them were synchronic and six heterochronmia. The 12, 32, 52 year survival rates were 63. 6 %, 27. 3 %, 9. 1 %, respectively. Conclusion 　More attention should be paid to MPMNs and early diagnosis and treatment might improve the therapeutic effect in these patients.