Abstract: Objective To evaluate the therapeutic efficacy of the i nterventional chemotherapy,which is used in comprehensive treatment of bulking a nd recurrent carcinoma of the cervix. Methods From June 1996 to D ecember 1998,there were 58 consecutive patients with cervical cancer in this stu dy of catheterization chemotherapy by internal iliac artery and radiation or sur gery.39 of 58 patients with primary and bulking cervical carcinoma's average di ameter are 5.6cm.19 patients with recurrent tumors were treated. Results Overall objective response rate 70.69% was achieved.The percentage of previously untreated patients was 89.74%;that of recurrent disease was 31.58% .The difference between these two groups was statistically significant.C onclusion In this series the interventional chemotherapy with radiation or surgery was very effective to bulking and recurrent cervix cancer.But it does not work to the patients with recent recurrent of irradiated,who have disease i n pelvic and locally failure cervix cancer.