| Citation: |
WANG Yuxiang, YANG Qiong, HE Ming, QIU Rong, LI Jing, QI Zhan, YAO Jifang, QIAO Xueying. Survival of Stage pT4 Esophageal Carcinoma Patients After Surgery[J]. Cancer Research on Prevention and Treatment, 2017, 44(7): 481-484. DOI: 10.3971/j.issn.1000-8578.2017.16.1317
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To retrospectively analyze the survival and its related factors of the patients with stage pT4 esophageal carcinoma (EC) after resection.
From Jan, 2008 to Dec, 2011, 77 patients with stage pT4N0-3M0 EC after resection were enrolled. Cox univariate and multivariate analysis were used to evaluate the postoperative survival and its related factors.
Until the end of follow-up, the 3-, 5-year survival rates and median overall survival (OS) were 39.0%, 35.3% and 24 months, respectively. Univariate analysis showed that tumor lesion and stage pN were associated with OS (P < 0.05); multivariate analysis revealed that stage pN was the only independent factor for OS. The 3-, 5-year progression-free survival (PFS) rates and median PFS were 43.6%, 34.6% and 21 months; univariate analysis showed that tumor lesion and stage pN were associated with PFS(P < 0.05); multivariate analysis revealed stage pN and removal lymph node number were the independent factors for PFS.
The survival of stage pT4N0-3M0 EC patients after surgery is poor. Stage pN is the most important independent factor for OS and PFS. Tumor lesion is also related with OS and PFS.
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