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DNA病毒介导肿瘤发生的表观遗传机制

胡玉倩, 郑义, 宁勇, 郗娟, 谢圣高

胡玉倩, 郑义, 宁勇, 郗娟, 谢圣高. DNA病毒介导肿瘤发生的表观遗传机制[J]. 肿瘤防治研究, 2016, 43(3): 230-233. DOI: 10.3971/j.issn.1000-8578.2016.03.013
引用本文: 胡玉倩, 郑义, 宁勇, 郗娟, 谢圣高. DNA病毒介导肿瘤发生的表观遗传机制[J]. 肿瘤防治研究, 2016, 43(3): 230-233. DOI: 10.3971/j.issn.1000-8578.2016.03.013
HU Yuqian, ZHENG Yi, NING Yong, XI Juan, XIE Shenggao. Epigenetic Mechanism of DNA Virus-mediated Carcinogenesis[J]. Cancer Research on Prevention and Treatment, 2016, 43(3): 230-233. DOI: 10.3971/j.issn.1000-8578.2016.03.013
Citation: HU Yuqian, ZHENG Yi, NING Yong, XI Juan, XIE Shenggao. Epigenetic Mechanism of DNA Virus-mediated Carcinogenesis[J]. Cancer Research on Prevention and Treatment, 2016, 43(3): 230-233. DOI: 10.3971/j.issn.1000-8578.2016.03.013

DNA病毒介导肿瘤发生的表观遗传机制

基金项目: 湖北省自然科学基金面上项目(2014CFB372)
详细信息
    作者简介:

    胡玉倩(1990-),女,硕士在读,主要从事肿瘤分子生物学研究

    通讯作者:

    郗娟,E-mail: xijuan_78love@126.com

    谢圣高,E-mail: xiesg100@163.com

  • 中图分类号: R730.231+.3

Epigenetic Mechanism of DNA Virus-mediated Carcinogenesis

  • 摘要: 许多病毒感染可导致肿瘤发生,这些病毒虽隶属于不同种属,但其进化出的分子干扰机制却有共通之处,即靶向调控与细胞生长和增殖相关的关键蛋白。病毒和宿主之间的相互作用也发生于表观遗传水平。本文对DNA病毒导致癌症发生的表观遗传机制进行综述。

     

    Abstract: Various kinds of virus could lead to carcinogenesis. Although those viruses belong to different viraceae, the molecular mechanisms they have evolved to cause tumor initiation show many similarities, which are targeting the key cellular proteins that regulate cell growth and proliferation. The interactions between virus and hosts occur at epigenetic level. This review summarizes the epigenetic mechanism of DNA virus proteins contributing to carcinogenesis.

     

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出版历程
  • 收稿日期:  2015-06-17
  • 修回日期:  2015-08-24
  • 刊出日期:  2016-03-24

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