Abstract: Objective To explore the effect of the informed status at different levels on the quality of life in lung cancer patients by survey. Methods The information was collected by questionnaire in lung cancer patients from June 2007 to December 2007.The FACT-L scale which was specialized for the evaluation of quality of life for lung cancer patients was used in this study. Results One hundred and fifteen patients were enrolled in this study,of those patients,the totally informed,partially informed and not informed patients account for 31.3%,49.6% and 19.1% respectively.The result indicated that different informed status significantly,affect the social/familial status and performance status(P value is 0.001 and 0.042 individually),and totally informed patients have obviously better social/familial status than partially informed and not informed patients.Further analysis showed that not informed patients have less influence on the social/familial life than that on the partially informed and totally informed patients (P value is 0.027 and 0.001 individually),the evaluation score in totally informed patients is higher than partially informed patients,but it failed to reach statistical significance (P=0.266). Conclusion At present,the percentage of informed hospitalized lung cancer patients is only 31.3% now days.Better informed status has positive influence on social/familial status.Thus,it is better to inform the patients of their disease at a suitable situation.