检测脑胶质瘤患者血、脑脊液SOD活力及LPO含量的意义

Detecting SOD activity and LPO content in blood and CSF in brain glioma patients

摘要: 目的　探讨脑胶质瘤患者血及脑脊液中SOD活力和LPO含量的变化及其临床意义。方法　应用黄嘌呤氧化酶法和硫代巴比妥酸法分别测定 32例脑胶质瘤患者术前、术后血液及脑脊液中SOD活力和LPO含量。结果　脑胶质瘤患者术前血液及脑脊液中SOD活力显著降低, 术后则明显升高 ;而LPO含量术前显著升高, 术后 3周基本恢复至正常水平。结论　临床监测脑胶质瘤患者血及脑脊液中SOD活力和LPO含量对其治疗、预后判断有一定的指导意义。

Abstract: Objective To study the changes of SOD activity and LPO content in blood and CSF in brain glioma patients. Methods Preoperation and postoperation SOD activity and LPO content were detected using the methods of xanthine oxdase and thiobarbituric acid in 32 patients with brain glioma. Results SOD activity in blood and CSF in patients with glioma was lower than that in the control group obviously before operation, and LPO content was higher than that in the control group significantly. SOD activity and LPO