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淋巴瘤患者静脉血栓栓塞症的研究进展

Progress of Venous Thromboembolism in Lymphoma Patients

  • 摘要: 血液恶性肿瘤患者易发生出凝血障碍,以急性白血病为代表,其中淋巴瘤出凝血障碍发生率也较高,凝血异常所致静脉血栓栓塞(VTE)是其死亡主要原因之一。淋巴瘤血栓栓塞症在非霍奇金淋巴瘤中发生率明显高于霍奇金淋巴瘤,VTE的发生可形成凝血瀑布从而促进肿瘤生长,提示患者疾病进展及病情恶化。淋巴瘤VTE发生的危险因素及相关特点可作为临床早期用药干预的依据从而改善患者预后,极大提高患者的生活质量。

     

    Abstract: Hematological malignant tumor patients are prone to coagulation disorders, represented by acute leukemia(AL), and the incidence of lymphoma coagulation disorders is also high and venous thromboembolism (VTE) caused by coagulopathy is one of the main causes of death. The incidence of lymphoma thromboembolism in non-Hodgkin lymphoma(NHL) is significantly higher than that in Hodgkin lymphoma(HL). The occurrence of VTE can form coagulation waterfall and promote tumor growth, indicating the disease progression and deterioration of patients. Risk factors and related characteristics of lymphoma VTE can be used as the basis for early clinical drug intervention to improve the prognosis of patients and greatly improve the quality of life.

     

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